Top 10 Largest Cities in Mississippi

Mississippi, located in the Deep South, is known as the “Magnolia State” for the abundant magnolia trees. The state has about 3 million people, with Jackson serving as both the capital and largest city, known for its history and cultural heritage.

10 Largest Cities in Mississippi


1. Jackson (Mississippi)

City Facts

  • County: Hinds
  • Area: 114.24 square miles
  • Population: 153,701 (2020 Census)
  • Area Codes: 601, 769
  • Zip Codes: 39201-39213, 39215-39216, 39218-39286
  • Latitude and Longitude: 32.2988° N, 90.1848° W

Location and History

Jackson, the capital city of Mississippi, is located in the central part of the state along the Pearl River. Founded in 1821, the city was named after Andrew Jackson, a prominent military leader and future U.S. President. Jackson’s early growth was fueled by its role as a transportation hub and its strategic location. Over time, it became the political and economic center of Mississippi, housing the state government and a variety of businesses. The city has faced economic and social challenges, including periods of significant civil unrest and economic downturns. However, Jackson remains a vital city with ongoing efforts to revitalize its downtown and improve its infrastructure.

Major Landmarks

  • Mississippi State Capitol: The seat of the state government, showcasing impressive architecture and historical significance.
  • Jackson Zoo: Home to a diverse collection of animals and a popular destination for families.
  • LeFleur’s Bluff State Park: Offers outdoor activities such as hiking and picnicking along the Pearl River.
  • Mississippi Museum of Art: Features regional and national art collections and exhibitions.

Major Highways

Jackson is well-connected by several major highways. Interstate 20 (I-20) runs east-west through the city, providing a route from Atlanta to Dallas. Interstate 55 (I-55) runs north-south, linking Jackson to Chicago and New Orleans. U.S. Highway 49 (US 49) provides a crucial north-south corridor connecting Jackson to the Gulf Coast. These highways facilitate regional and long-distance travel, supporting Jackson’s role as a central hub in Mississippi.

2. Gulfport (Mississippi)

City Facts

  • County: Harrison
  • Area: 55.43 square miles
  • Population: 72,012 (2020 Census)
  • Area Codes: 228
  • Zip Codes: 39501-39507, 39530
  • Latitude and Longitude: 30.3674° N, 89.0928° W

Location and History

Gulfport, located on the Gulf of Mexico in Harrison County, was founded in 1898 and is the second-largest city in Mississippi. It developed as a port and shipping center due to its strategic location on the Gulf Coast. The city has a history of economic ups and downs, heavily influenced by natural disasters like Hurricane Katrina in 2005, which caused extensive damage. Despite these challenges, Gulfport has rebuilt and continues to thrive as a major center for commerce, tourism, and recreation along the Gulf Coast.

Major Landmarks

  • Gulfport Harbor Lights Winter Festival: An annual event featuring holiday lights and festivities.
  • Ship Island: Accessible by ferry, offering beaches and historic forts.
  • Gulfport Beach: A popular destination for swimming and sunbathing.
  • The Island View Casino Resort: A major casino and resort providing entertainment and accommodations.

Major Highways

Gulfport is served by several key highways that support regional travel and commerce. Interstate 10 (I-10) runs east-west through the city, connecting it to New Orleans and Mobile. U.S. Highway 49 (US 49) runs north-south, linking Gulfport to Jackson and other inland areas. Additionally, U.S. Highway 90 (US 90) runs parallel to the Gulf Coast, providing scenic coastal access and connecting Gulfport to other beach communities. These highways are crucial for maintaining Gulfport’s economic and tourism activities.

3. Biloxi (Mississippi)

City Facts

  • County: Harrison
  • Area: 49.48 square miles
  • Population: 49,088 (2020 Census)
  • Area Codes: 228
  • Zip Codes: 39530-39532, 39535
  • Latitude and Longitude: 30.3960° N, 88.8850° W

Location and History

Biloxi, situated on the Gulf of Mexico in Harrison County, has a history dating back to the early 18th century. Originally founded by French settlers, Biloxi developed as a fishing and maritime hub. The city became known for its seafood industry and tourism, particularly its casinos and beachfront resorts. Biloxi has faced challenges from natural disasters, including Hurricane Katrina, which caused significant damage. Despite these setbacks, the city has recovered and continues to be a popular destination for tourists seeking entertainment and relaxation along the Gulf Coast.

Major Landmarks

  • Biloxi Lighthouse: An iconic historic lighthouse that serves as a symbol of the city.
  • Beau Rivage Resort & Casino: A major casino and hotel offering gaming, entertainment, and dining.
  • Biloxi Maritime and Seafood Industry Museum: Showcases the city’s maritime history and seafood industry.
  • Gulf Islands National Seashore: Offers beautiful beaches and recreational opportunities.

Major Highways

Biloxi is well-connected by major highways that facilitate travel and commerce. Interstate 10 (I-10) runs through the city, providing east-west access to New Orleans and Mobile. U.S. Highway 90 (US 90) runs along the Gulf Coast, offering scenic views and connecting Biloxi to other coastal communities. Additionally, U.S. Highway 49 (US 49) connects Biloxi to Jackson and other inland areas. These highways support Biloxi’s tourism industry and regional connectivity.

4. Hattiesburg (Mississippi)

City Facts

  • County: Forrest
  • Area: 56.34 square miles
  • Population: 49,331 (2020 Census)
  • Area Codes: 601, 769
  • Zip Codes: 39401-39407
  • Latitude and Longitude: 31.3271° N, 89.2903° W

Location and History

Hattiesburg, located in southern Mississippi, was founded in 1882. The city’s location at the intersection of several railroads made it a vital transportation hub in the late 19th and early 20th centuries. Hattiesburg has a diverse economy with strong sectors in education, healthcare, and manufacturing. The presence of the University of Southern Mississippi has significantly influenced the city’s cultural and economic development. Hattiesburg continues to grow as a regional center for business and education.

Major Landmarks

  • University of Southern Mississippi: A major public research university with a vibrant campus.
  • Hattiesburg Zoo: Features a variety of animal exhibits and educational programs.
  • Hattiesburg Historic Depot: A restored railroad depot reflecting the city’s transportation history.
  • Paul B. Johnson State Park: Offers outdoor activities like fishing, hiking, and camping.

Major Highways

Hattiesburg is connected by several major highways that support regional and local travel. Interstate 59 (I-59) runs north-south through the city, linking it to New Orleans and Meridian. U.S. Highway 49 (US 49) provides a north-south corridor connecting Hattiesburg to Jackson and the Gulf Coast. U.S. Highway 98 (US 98) runs east-west, offering access to the coast and other inland areas. These highways are essential for maintaining Hattiesburg’s role as a regional business and transportation center.

5. Tupelo (Mississippi)

City Facts

  • County: Lee
  • Area: 60.36 square miles
  • Population: 38,141 (2020 Census)
  • Area Codes: 662
  • Zip Codes: 38801-38804
  • Latitude and Longitude: 34.2575° N, 88.7030° W

Location and History

Tupelo, located in northeastern Mississippi, is known for its rich cultural heritage and historical significance. Founded in the early 19th century, Tupelo became a key center for agriculture and trade in the region. The city is notably the birthplace of Elvis Presley, which has contributed to its cultural and tourism appeal. Tupelo has grown steadily, with a diverse economy that includes manufacturing, healthcare, and retail. The city maintains a blend of historical charm and modern development.

Major Landmarks

  • Elvis Presley Birthplace: A museum and park dedicated to the life and legacy of Elvis Presley.
  • Tupelo Buffalo Park and Zoo: Offers a range of animal exhibits and recreational activities.
  • Tupelo Automobile Museum: Features a collection of classic and vintage cars.
  • Natchez Trace Parkway: A scenic drive passing near Tupelo, offering historical and natural attractions.

Major Highways

Tupelo is served by key highways that support regional travel. U.S. Highway 45 (US 45) runs north-south through the city, connecting Tupelo to Memphis and Meridian. U.S. Highway 78 (US 78) provides an east-west route linking Tupelo to Birmingham and Memphis. Additionally, U.S. Highway 82 (US 82) connects Tupelo to other parts of Mississippi. These highways are important for transportation and economic activities in Tupelo and the surrounding region.

6. Southaven (Mississippi)

City Facts

  • County: DeSoto
  • Area: 34.61 square miles
  • Population: 58,897 (2020 Census)
  • Area Codes: 662
  • Zip Codes: 38671-38672
  • Latitude and Longitude: 34.9870° N, 90.0140° W

Location and History

Southaven, located in northern Mississippi near the Tennessee border, is a rapidly growing city with a strong suburban appeal. Established in the early 20th century, Southaven has seen significant growth in recent decades due to its proximity to Memphis, Tennessee. The city has a diverse economy with a mix of retail, healthcare, and manufacturing sectors. Southaven is known for its family-friendly atmosphere and well-developed infrastructure, contributing to its appeal as a desirable place to live.

Major Landmarks

  • Southaven Towne Center: A major shopping and dining destination.
  • DeSoto Civic Center: Hosts a variety of events, including concerts and sports.
  • Tanger Outlets: Offers a wide range of retail stores and dining options.
  • Latimer Lakes Park: Provides recreational facilities and scenic walking trails.

Major Highways

Southaven is well-connected by major highways that facilitate regional and interstate travel. Interstate 55 (I-55) runs north-south through the city, linking it to Memphis and Jackson. Interstate 269 (I-269) forms a ring around the Memphis metropolitan area, providing access to various regional destinations. U.S. Highway 51 (US 51) runs through Southaven, offering additional connectivity. These highways support Southaven’s growth and its integration with the larger Memphis metropolitan area.

7. Meridian (Mississippi)

City Facts

  • County: Lauderdale
  • Area: 45.58 square miles
  • Population: 37,200 (2020 Census)
  • Area Codes: 601, 769
  • Zip Codes: 39301-39309
  • Latitude and Longitude: 32.3643° N, 88.7030° W

Location and History

Meridian, located in eastern Mississippi, is known for its role as a major railway and transportation hub. Founded in the early 19th century, Meridian’s strategic location at the intersection of several railroads spurred its growth as an industrial and commercial center. The city has a rich cultural heritage and is recognized for its historical architecture and vibrant arts scene. Meridian continues to serve as an important regional center for business and culture in Mississippi.

Major Landmarks

  • Meridian Museum of Art: Features a range of visual art exhibits and educational programs.
  • Davis Park: A large park offering recreational facilities and walking trails.
  • Meridian Railroad Museum: Highlights the city’s rail history and heritage.
  • The Grand Opera House: A historic venue for performing arts and entertainment.

Major Highways

Meridian is accessible via several major highways that support regional and interstate travel. Interstate 20 (I-20) runs east-west through the city, linking Meridian to Jackson and Birmingham. Interstate 59 (I-59) runs north-south, connecting Meridian to New Orleans and Hattiesburg. U.S. Highway 11 (US 11) runs parallel to I-59, providing additional connectivity. These highways facilitate Meridian’s role as a transportation and business center in eastern Mississippi.

8. Olive Branch (Mississippi)

City Facts

  • County: DeSoto
  • Area: 37.71 square miles
  • Population: 37,209 (2020 Census)
  • Area Codes: 662
  • Zip Codes: 38654-38661
  • Latitude and Longitude: 34.9735° N, 89.8274° W

Location and History

Olive Branch, located in northern Mississippi near Memphis, Tennessee, is a growing suburb known for its family-friendly environment and strong community focus. Established in the early 19th century, Olive Branch has experienced significant growth due to its proximity to Memphis and its appeal as a residential area. The city has developed a diverse economy with a focus on retail, education, and services, and continues to attract new residents seeking suburban living with access to metropolitan amenities.

Major Landmarks

  • Olive Branch City Park: Provides recreational facilities and green space for residents.
  • Cherokee Valley Golf Club: A popular destination for golf enthusiasts.
  • Olive Branch Public Library: Offers a range of resources and community programs.
  • The Historic Olive Branch Depot: Reflects the city’s rail history and heritage.

Major Highways

Olive Branch is connected by major highways that support regional travel and commerce. Interstate 22 (I-22) runs through the city, linking it to Memphis and Birmingham. U.S. Highway 78 (US 78) also passes through Olive Branch, providing an east-west corridor connecting the city to other regional destinations. Additionally, U.S. Highway 51 (US 51) runs near Olive Branch, offering further connectivity. These highways facilitate access to the Memphis metropolitan area and support Olive Branch’s growth as a suburban community.

9. Pascagoula (Mississippi)

City Facts

  • County: Jackson
  • Area: 19.27 square miles
  • Population: 21,552 (2020 Census)
  • Area Codes: 228
  • Zip Codes: 39567-39581
  • Latitude and Longitude: 30.3650° N, 88.5432° W

Location and History

Pascagoula, located on the Gulf Coast of Mississippi, is known for its maritime heritage and role as a port city. Founded in the early 19th century, Pascagoula developed around its shipbuilding industry and seafood processing. The city is home to a significant shipyard and is a key player in the region’s maritime economy. Pascagoula has a rich cultural history and continues to be a center for industry and tourism along the Gulf Coast.

Major Landmarks

  • Pascagoula Beach: A popular spot for swimming and recreational activities.
  • Pascagoula River Audubon Center: Offers educational programs and natural exhibits.
  • Ship Island: Accessible by ferry, featuring beaches and historic sites.
  • Moss Point Historic Museum: Showcases the history and heritage of the local area.

Major Highways

Pascagoula is well-served by major highways that support regional travel and commerce. U.S. Highway 90 (US 90) runs along the Gulf Coast, providing scenic access to other coastal cities and attractions. Interstate 10 (I-10) runs through the city, linking Pascagoula to New Orleans and Mobile. Additionally, U.S. Highway 63 (US 63) connects Pascagoula to inland areas and regional destinations. These highways are vital for maintaining Pascagoula’s economic activities and connectivity.

10. Brookhaven (Mississippi)

City Facts

  • County: Lincoln
  • Area: 11.23 square miles
  • Population: 13,223 (2020 Census)
  • Area Codes: 601, 769
  • Zip Codes: 39601-39603
  • Latitude and Longitude: 31.5846° N, 90.4488° W

Location and History

Brookhaven, located in southwestern Mississippi, is known for its small-town charm and historical significance. Founded in the late 19th century, the city has a rich history tied to agriculture and railroads. Brookhaven has evolved into a regional center for commerce and services, serving as a hub for surrounding communities. The city maintains a strong sense of local heritage and community, with a focus on preserving its historical landmarks and promoting economic development.

Major Landmarks

  • Brookhaven-Lincoln County Chamber of Commerce: Promotes local businesses and community events.
  • Brookhaven City Park: Offers recreational facilities and green space.
  • Old Brookhaven Historic District: Features well-preserved historic homes and buildings.
  • Lincoln County Public Library: Provides resources and programs for the community.

Major Highways

Brookhaven is connected by major highways that facilitate regional travel and commerce. U.S. Highway 51 (US 51) runs north-south through the city, linking Brookhaven to Jackson and New Orleans. U.S. Highway 84 (US 84) runs east-west, providing access to Hattiesburg and other regional destinations. Additionally, Mississippi Highway 550 (MS 550) offers connectivity to surrounding areas. These highways support Brookhaven’s role as a regional center and facilitate travel within southwestern Mississippi.