Missouri, located in the Midwest, is the “Show-Me State,” a nickname reflecting the residents’ practicality and skepticism. Missouri has 6.2 million people. Jefferson City is the capital, while Kansas City, known for its jazz music and barbecue, is the largest city.
10 Largest Cities in Missouri
1. Kansas City (Missouri)
City Facts
- County: Jackson, Clay, Platte, and Cass
- Area: 319.03 sq mi
- Population: Approximately 507,000
- Area Codes: 816, 913
- Zip Codes: 64101, 64102, 64105, 64106, 64108, 64109, 64110, 64111, 64112, 64113, 64114, 64116, 64117, 64118, 64119, 64120, 64121, 64123, 64124, 64125, 64126, 64127, 64128, 64129, 64130, 64131, 64132, 64133, 64134, 64136, 64137, 64138, 64139, 64145, 64146, 64147, 64148, 64149, 64150, 64151, 64152, 64153, 64154, 64155, 64156, 64157, 64158, 64161, 64162, 64163, 64164, 64165, 64166, 64167, 64168, 64170
- Latitude/Longitude: 39.0997° N, 94.5786° W
Location and History
Kansas City, located in western Missouri, is known for its vibrant arts scene, jazz heritage, and rich history. Founded in the early 19th century, Kansas City grew rapidly as a trading and transportation hub due to its strategic location at the confluence of the Missouri and Kansas rivers. It became a major cattle and railroad center, which spurred its growth into one of the largest cities in the state. The city is renowned for its historic architecture, diverse neighborhoods, and significant cultural contributions.
Major Landmarks
- Union Station: A historic train station with a museum, restaurants, and events.
- National World War I Museum and Memorial: Offers extensive exhibits and commemorates the First World War.
- Kansas City Zoo: Features a variety of animal exhibits and educational programs.
- Country Club Plaza: A shopping district known for its Spanish-inspired architecture and upscale stores.
- Kauffman Center for the Performing Arts: A modern venue hosting a range of performing arts, including ballet and symphony.
Major Highways
Kansas City is a major transportation hub with several key highways intersecting the city. Interstate 70 (I-70) runs east-west, connecting Kansas City to St. Louis and Denver. Interstate 35 (I-35) runs north-south, linking the city to cities such as Minneapolis and Dallas. Interstate 670 (I-670) provides a bypass around downtown, facilitating easier access to the surrounding areas. Additionally, Interstate 470 (I-470) serves as a bypass to the southeastern parts of the metropolitan area. These highways ensure smooth travel and connectivity within the region and beyond.
2. St. Louis (Missouri)
City Facts
- County: City of St. Louis (Independent)
- Area: 66.22 sq mi
- Population: Approximately 293,000
- Area Codes: 314, 636
- Zip Codes: 63101, 63102, 63103, 63104, 63105, 63106, 63107, 63108, 63109, 63110, 63111, 63112, 63113, 63115, 63116, 63118, 63120, 63121, 63122, 63123, 63124, 63125, 63126, 63127, 63128, 63129, 63130, 63131, 63132, 63133, 63134, 63135, 63136, 63137, 63138, 63139, 63141, 63143, 63144, 63145, 63146, 63147, 63149
- Latitude/Longitude: 38.6270° N, 90.1994° W
Location and History
St. Louis, located on the western bank of the Mississippi River, is known for its historic significance and cultural heritage. Founded in 1764 by French explorers, the city grew as a key port and gateway to the west during the 19th century. It became a major center for industry and commerce, known for its contributions to music, particularly jazz and blues. Today, St. Louis is recognized for its historic landmarks, diverse cultural institutions, and its role as a significant Midwestern city.
Major Landmarks
- Gateway Arch: An iconic 630-foot monument symbolizing the westward expansion of the United States.
- Forest Park: A large urban park home to the St. Louis Zoo, Art Museum, and Science Center.
- St. Louis Zoo: Offers extensive animal exhibits and educational programs, free to the public.
- The Missouri Botanical Garden: Features beautiful landscapes and plant collections.
- Anheuser-Busch Brewery: Historic brewery offering tours and a look into its brewing process.
Major Highways
St. Louis is a key transportation center with several major highways running through the city. Interstate 64 (I-64) runs east-west, connecting St. Louis to cities such as Louisville and Richmond. Interstate 44 (I-44) runs southwest, linking St. Louis to Tulsa and other destinations. Interstate 55 (I-55) runs north-south, connecting St. Louis to Chicago and New Orleans. Additionally, Interstate 70 (I-70) runs east from St. Louis, providing access to other major cities and regions. These highways support extensive regional and national connectivity.
3. Springfield (Missouri)
City Facts
- County: Greene
- Area: 82.58 sq mi
- Population: Approximately 170,000
- Area Codes: 417
- Zip Codes: 65801, 65802, 65803, 65804, 65805, 65806, 65807, 65809, 65810, 65814, 65817
- Latitude/Longitude: 37.2089° N, 93.2923° W
Location and History
Springfield, located in southwestern Missouri, is known for its historical significance and role as a regional economic and cultural center. Founded in 1838, Springfield became an important trade and transportation hub due to its location on the railroads and major highways. The city is famously known as the birthplace of Route 66, which contributed to its historical and cultural significance. Springfield has developed into a vibrant city with a diverse economy and a range of cultural attractions.
Major Landmarks
- National Museum of Military History: Showcases artifacts and exhibits related to military history.
- Springfield Botanical Gardens: Offers a variety of gardens and outdoor spaces for visitors.
- The Wonders of Wildlife National Museum and Aquarium: Features exhibits on wildlife and aquatic life.
- Bass Pro Shops at the Pyramid: A major retail and entertainment complex with an observation deck.
- Dickerson Park Zoo: Provides animal exhibits and educational programs for the public.
Major Highways
Springfield is well-connected by several major highways that facilitate travel throughout the region. Interstate 44 (I-44) runs through the city, providing a route between St. Louis and Tulsa. U.S. Route 65 runs north-south, linking Springfield to other regional cities. Additionally, U.S. Route 60 runs east-west, connecting Springfield to destinations in both directions. These highways support regional travel and access to Springfield’s key economic and cultural areas.
4. Columbia (Missouri)
City Facts
- County: Boone
- Area: 63.89 sq mi
- Population: Approximately 130,000
- Area Codes: 573
- Zip Codes: 65201, 65202, 65203, 65205, 65211
- Latitude/Longitude: 38.9517° N, 92.3341° W
Location and History
Columbia, located in central Missouri, is known as a major university town and cultural hub. Founded in 1821, Columbia is home to the University of Missouri, which significantly influences the city’s economy and cultural life. The city has grown around the university and has developed a vibrant cultural scene, with numerous events, museums, and recreational facilities. Columbia’s historical roots and educational institutions contribute to its reputation as an important regional center.
Major Landmarks
- University of Missouri: Known for its historic campus, research facilities, and the Mizzou Tigers sports teams.
- Rock Bridge Memorial State Park: Offers hiking trails and natural scenery, including the Devil’s Icebox cave.
- Museum of Art and Archaeology: Features exhibits on art, history, and archaeology.
- Columbia Mall: A major retail center with a range of shops and dining options.
- Stephens Lake Park: A popular park with walking trails, a lake, and recreational facilities.
Major Highways
Columbia is well-connected by major highways that support regional and national travel. Interstate 70 (I-70) runs east-west, providing access to cities such as St. Louis and Kansas City. U.S. Route 63 runs north-south, linking Columbia to other parts of Missouri and extending towards northern regions. Additionally, U.S. Route 54 runs east-west, connecting Columbia to other regional destinations. These highways ensure that Columbia remains accessible and well-connected within the broader regional and national transportation network.
5. Lee’s Summit (Missouri)
City Facts
- County: Jackson, Cass
- Area: 64.12 sq mi
- Population: Approximately 110,000
- Area Codes: 816, 913
- Zip Codes: 64063, 64064, 64081, 64082
- Latitude/Longitude: 38.9106° N, 94.3824° W
Location and History
Lee’s Summit, located in the Kansas City metropolitan area, is known for its suburban charm and growing community. Founded in 1865, the city was named after the Confederate General Robert E. Lee and has grown from a small railway town into a significant suburban community. Lee’s Summit is recognized for its strong local economy, high quality of life, and family-friendly environment. Its development has been driven by its proximity to Kansas City and its role as a key suburban area.
Major Landmarks
- Downtown Lee’s Summit: Features historic buildings, local shops, and restaurants.
- Summit Waves: A water park offering recreational and family-friendly activities.
- Missouri Town 1855: An outdoor museum depicting life in the mid-19th century.
- The Legacy Park: Offers trails, playgrounds, and sports facilities.
- Railroad Park: Celebrates the city’s railway heritage with historical displays and events.
Major Highways
Lee’s Summit benefits from its location along several major highways that facilitate regional travel. Interstate 470 (I-470) serves as a bypass around the city, linking it to the broader Kansas City metropolitan area. U.S. Route 50 runs through Lee’s Summit, providing access to various destinations both east and west. Additionally, Interstate 35 (I-35) runs to the west of the city, connecting Lee’s Summit to Kansas City and other points further south. These highways ensure smooth transportation and connectivity to the surrounding areas.
6. Joplin (Missouri)
City Facts
- County: Jasper, Newton
- Area: 45.93 sq mi
- Population: Approximately 53,000
- Area Codes: 417
- Zip Codes: 64801, 64804, 64870
- Latitude/Longitude: 37.0842° N, 94.5137° W
Location and History
Joplin, located in southwestern Missouri, is known for its historical significance in the mining industry and its role as a regional economic center. Founded in the late 19th century, Joplin became a major hub for lead and zinc mining, which drove its early growth. The city has evolved over the years into a vibrant community with a strong economy, cultural attractions, and a rich history. Joplin’s development has been influenced by its industrial past and its strategic location on major transportation routes.
Major Landmarks
- Joplin Museum Complex: Includes the Joplin History and Mineral Museum and offers insights into local history and mining.
- Cunningham Park: Features walking trails, playgrounds, and sports facilities.
- Ruby Jack Golf Course: A popular golfing destination with scenic views and well-maintained greens.
- Wildcat Glades Conservation & Audubon Center: Provides educational programs and outdoor activities focused on local wildlife.
- Joplin Little Theatre: Hosts a range of theatrical performances and community events.
Major Highways
Joplin is well-connected by several major highways that support transportation and regional connectivity. Interstate 44 (I-44) runs through the city, providing a route between St. Louis and Tulsa. U.S. Route 66, a historic route, runs through Joplin, adding to its historical significance. Additionally, U.S. Route 49 runs through the area, linking Joplin to other regional destinations. These highways ensure efficient transportation and connectivity for Joplin’s residents and visitors.
7. St. Joseph (Missouri)
City Facts
- County: Buchanan
- Area: 43.48 sq mi
- Population: Approximately 77,000
- Area Codes: 816
- Zip Codes: 64501, 64502, 64503, 64504, 64505, 64506, 64507
- Latitude/Longitude: 39.7684° N, 94.8466° W
Location and History
St. Joseph, located in northwest Missouri along the Missouri River, is known for its historical significance in the westward expansion of the United States. Founded in 1843, St. Joseph became an important starting point for the Pony Express and a key trading center. The city played a significant role in the development of the American West and has retained much of its historical charm. Today, St. Joseph is known for its rich history and cultural attractions.
Major Landmarks
- Pony Express National Museum: Highlights the history of the Pony Express and its impact on American history.
- St. Joseph Museum: Offers exhibits on local history, art, and culture.
- Krug Park: Features beautiful gardens, a lagoon, and recreational facilities.
- Wyeth-Tootle Mansion: A historic home showcasing period furnishings and local history.
- Albrecht-Kemper Museum of Art: Features a diverse collection of American art and rotating exhibitions.
Major Highways
St. Joseph is connected by several major highways that support regional travel and commerce. Interstate 29 (I-29) runs north-south, linking St. Joseph to Kansas City and other destinations. U.S. Route 36 runs east-west, connecting the city to St. Louis and other regional points. Additionally, U.S. Route 169 runs through St. Joseph, providing further connectivity to surrounding areas. These highways facilitate easy access to and from St. Joseph, supporting its role as a regional hub.
8. Lee’s Summit (Missouri)
City Facts
- County: Jackson, Cass
- Area: 64.12 sq mi
- Population: Approximately 110,000
- Area Codes: 816, 913
- Zip Codes: 64063, 64064, 64081, 64082
- Latitude/Longitude: 38.9106° N, 94.3824° W
Location and History
Lee’s Summit is a growing city in the Kansas City metropolitan area known for its suburban charm and family-friendly environment. Established in 1865, the city was named after the Confederate General Robert E. Lee. Lee’s Summit has transformed from a small railroad town into a significant suburban community with a thriving economy and vibrant cultural scene. Its proximity to Kansas City has contributed to its growth and development, making it a desirable place for residents seeking a blend of suburban and urban amenities.
Major Landmarks
- Downtown Lee’s Summit: Features historic architecture, local shops, and a variety of dining options.
- Summit Waves: A popular water park with slides, a lazy river, and other aquatic attractions.
- Missouri Town 1855: An outdoor museum showcasing mid-19th-century rural life.
- The Legacy Park: Offers walking trails, playgrounds, and sports facilities for community use.
- Railroad Park: Celebrates the city’s railway history with displays and events.
Major Highways
Lee’s Summit is strategically located with several major highways that facilitate regional and local travel. Interstate 470 (I-470) runs around the city, connecting it to other parts of the Kansas City metropolitan area. U.S. Route 50 traverses the city, providing a route east towards cities such as Warrensburg and west towards larger regional destinations. Additionally, Interstate 35 (I-35) runs nearby, linking Lee’s Summit to Kansas City and other points further south. These highways ensure efficient transportation and connectivity for Lee’s Summit’s residents and visitors.
9. O’Fallon (Missouri)
City Facts
- County: St. Charles
- Area: 31.60 sq mi
- Population: Approximately 90,000
- Area Codes: 636
- Zip Codes: 63366, 63368
- Latitude/Longitude: 38.8102° N, 90.7215° W
Location and History
O’Fallon, located in St. Charles County, is a growing city in the Greater St. Louis area. Established in the early 19th century, O’Fallon has developed into one of the fastest-growing cities in Missouri. The city’s growth has been driven by its proximity to St. Louis and its appeal as a suburban community with a high quality of life. O’Fallon offers a mix of residential, commercial, and recreational amenities, contributing to its reputation as a desirable place to live and work.
Major Landmarks
- O’Fallon Historic Museum: Provides insights into the city’s history and heritage.
- The Crossing at Northwest: A shopping and dining destination with a variety of stores and restaurants.
- Civic Park: Features sports fields, playgrounds, and a community center.
- Dames Park: A park with walking trails, picnic areas, and sports facilities.
- O’Fallon Family YMCA: Offers a range of recreational and fitness programs for residents.
Major Highways
O’Fallon is well-connected by several major highways that support regional and local transportation. Interstate 70 (I-70) runs through the city, providing a route between St. Louis and other destinations. U.S. Route 40 runs parallel to I-70, offering additional connectivity to surrounding areas. Additionally, U.S. Route 61 runs through the city, linking O’Fallon to other regional points. These highways facilitate efficient travel and access to O’Fallon’s key areas and amenities.
10. Jefferson City (Missouri)
City Facts
- County: Cole
- Area: 33.14 sq mi
- Population: Approximately 43,000
- Area Codes: 573
- Zip Codes: 65101, 65109, 65110
- Latitude/Longitude: 38.5767° N, 92.1735° W
Location and History
Jefferson City, the state capital of Missouri, is located in central Missouri along the Missouri River. Founded in 1821, the city was chosen as the state capital due to its central location. Jefferson City has a rich history related to its role in state government and politics. The city is known for its historic buildings, including the Missouri State Capitol, and its role as a hub for state government activities. Jefferson City has developed into a key center for political and cultural life in Missouri.
Major Landmarks
- Missouri State Capitol: The seat of Missouri’s government, featuring historic architecture and public tours.
- Governor’s Mansion: The official residence of the Missouri governor, open for tours and events.
- Jefferson Landing State Historic Site: Preserves historic buildings related to the city’s early history.
- Lewis and Clark Monument: Commemorates the explorers’ journey and their impact on the region.
- Runge Nature Center: Offers educational programs and nature trails for visitors.
Major Highways
Jefferson City is connected by several major highways that facilitate transportation within the region. Interstate 63 (I-63) runs through the city, providing north-south connectivity. U.S. Route 50 runs east-west, linking Jefferson City to St. Louis and other regional destinations. Additionally, U.S. Route 54 connects the city to points both east and west. These highways ensure efficient travel and access to the city’s government, cultural, and recreational facilities.