Top 10 Largest Cities in South Carolina

South Carolina, in the southeastern U.S., is the “Palmetto State,” referencing the state tree. South Carolina has 5.4 million people. Columbia is the capital, and Charleston, known for its history and charm, is the largest city.

10 Largest Cities in South Carolina


1. Charleston (South Carolina)

City Facts

  • County: Charleston
  • Area: 127.50 sq mi
  • Population: Approximately 150,000
  • Area Codes: 843
  • Zip Codes: 29401, 29403, 29404, 29405, 29407, 29409, 29412, 29414, 29425
  • Latitude/Longitude: 32.7765° N, 79.9311° W

Location and History

Charleston, located on the coast of South Carolina along the Atlantic Ocean, is known for its historic charm and rich cultural heritage. Founded in 1670, Charleston was initially named Charles Town in honor of King Charles II of England. The city played a significant role in American history, particularly during the American Revolution and the Civil War. Its well-preserved historic district features cobblestone streets, antebellum architecture, and historic landmarks. Charleston is celebrated for its vibrant cultural scene, cuisine, and historic preservation efforts, making it a popular destination for tourists and history enthusiasts alike.

Major Landmarks

  • Historic Downtown Charleston: Features preserved 18th and 19th-century architecture and historic homes.
  • The Battery: A historic promenade offering views of historic mansions and cannons from the Civil War.
  • Magnolia Plantation and Gardens: One of the oldest public gardens in America, known for its beautiful landscapes and historical significance.
  • Fort Sumter National Monument: The site where the first shots of the Civil War were fired.
  • Charleston City Market: A historic market offering a range of local crafts, food, and souvenirs.

Major Highways

Charleston is served by several major highways that facilitate regional and interstate travel. Interstate 26 (I-26) runs west from Charleston, connecting the city to Columbia and other inland destinations. U.S. Route 17 (US 17) runs north-south along the coast, linking Charleston to cities such as Myrtle Beach and Savannah, Georgia. Interstate 95 (I-95) is accessible via U.S. Route 17, providing north-south connectivity along the eastern seaboard. These highways are vital for transportation and support Charleston’s role as a major port city and tourist destination.

2. Columbia (South Carolina)

City Facts

  • County: Richland
  • Area: 133.14 sq mi
  • Population: Approximately 140,000
  • Area Codes: 803
  • Zip Codes: 29201, 29203, 29204, 29205, 29206, 29209, 29210, 29212, 29229
  • Latitude/Longitude: 34.0007° N, 81.0348° W

Location and History

Columbia, the capital of South Carolina, is located in the central part of the state along the Congaree River. Founded in 1786, it was chosen as the state capital due to its central location, which was intended to be more accessible to residents across the state. Columbia has evolved from a small settlement into a vibrant city known for its government buildings, educational institutions, and cultural attractions. It is home to the University of South Carolina and has a growing economy driven by education, healthcare, and government services.

Major Landmarks

  • South Carolina State House: The seat of the state government, known for its historic architecture and surrounding grounds.
  • Columbia Museum of Art: Features a diverse collection of art, including American, European, and contemporary works.
  • Riverbanks Zoo & Garden: Offers a range of animal exhibits, botanical gardens, and educational programs.
  • Congaree National Park: A nearby park known for its old-growth bottomland hardwood forest and recreational opportunities.
  • Historic Columbia Foundation: Provides tours and educational programs on the city’s history and preservation efforts.

Major Highways

Columbia is well-connected by major highways that support both regional and interstate travel. Interstate 20 (I-20) runs east-west through the city, linking Columbia to Augusta, Georgia, and the western parts of South Carolina. Interstate 26 (I-26) runs north-south, connecting Columbia to Charleston and the upstate region of South Carolina. Interstate 77 (I-77) also runs north-south, providing access to Charlotte, North Carolina, and the northern parts of South Carolina. These highways are crucial for transportation and support Columbia’s role as the state capital and a regional economic center.

3. North Charleston (South Carolina)

City Facts

  • County: Charleston
  • Area: 76.60 sq mi
  • Population: Approximately 120,000
  • Area Codes: 843
  • Zip Codes: 29405, 29406, 29418, 29420, 29456
  • Latitude/Longitude: 32.8551° N, 80.0453° W

Location and History

North Charleston, located in the Charleston metropolitan area, is a major industrial and commercial hub. Incorporated in 1972, it has grown rapidly due to its strategic location and economic development. The city serves as a key center for manufacturing, aviation, and transportation, with significant employers including the Charleston International Airport and the North Charleston Coliseum. North Charleston’s growth has been driven by its proximity to the port of Charleston and its role in the regional economy.

Major Landmarks

  • North Charleston Coliseum: A multi-purpose arena hosting concerts, sports events, and other performances.
  • Charleston International Airport: The primary airport serving the Charleston area and a major economic driver for the city.
  • Riverfront Park: A scenic park offering walking trails, playgrounds, and views of the Cooper River.
  • The Charleston Area Convention Center: A facility that hosts various conventions, trade shows, and community events.
  • H.L. Hunley Submarine: A historic Civil War-era submarine displayed at the Warren Lasch Conservation Center.

Major Highways

North Charleston is served by several key highways that facilitate regional and interstate travel. Interstate 26 (I-26) runs east-west through the city, linking North Charleston to Columbia and Charleston. Interstate 526 (I-526), also known as the Mark Clark Expressway, provides a bypass route around the city and connects to various parts of the Charleston metropolitan area. U.S. Route 78 (US 78) runs west from North Charleston, offering connectivity to Summerville and the upstate regions of South Carolina. These highways are essential for transportation and support North Charleston’s economic growth and regional connectivity.

4. Mount Pleasant (South Carolina)

City Facts

  • County: Charleston
  • Area: 42.17 sq mi
  • Population: Approximately 90,000
  • Area Codes: 843
  • Zip Codes: 29464, 29465, 29466, 29492
  • Latitude/Longitude: 32.7910° N, 79.8628° W

Location and History

Mount Pleasant is located just across the Cooper River from Charleston and is known for its picturesque setting and suburban charm. Established in the early 19th century, the city has grown from a small village into a thriving suburban community. Mount Pleasant is recognized for its historic homes, family-friendly environment, and access to beautiful waterfront areas. The city’s growth has been driven by its proximity to Charleston and its appeal as a desirable place to live.

Major Landmarks

  • Patriots Point Naval & Maritime Museum: Features historic naval ships, including the USS Yorktown aircraft carrier.
  • Mount Pleasant Memorial Waterfront Park: A park with walking trails, fishing pier, and scenic views of the Ravenel Bridge.
  • Old Village Historic District: A preserved area with historic homes and charming streets.
  • Shem Creek: A popular spot for dining, boating, and viewing local wildlife.
  • Palmetto Islands County Park: Offers recreational activities, including trails, picnic areas, and a water park.

Major Highways

Mount Pleasant is well-connected by several major highways that facilitate regional and interstate travel. U.S. Route 17 (US 17) runs north-south through the city, linking Mount Pleasant to Charleston and the northern coastal regions of South Carolina. Interstate 526 (I-526), also known as the Mark Clark Expressway, provides a bypass route around Charleston and connects Mount Pleasant to the airport and other parts of the Charleston metropolitan area. These highways are crucial for transportation and support Mount Pleasant’s role as a key suburban community in the Charleston area.

5. Rock Hill (South Carolina)

City Facts

  • County: York
  • Area: 37.20 sq mi
  • Population: Approximately 75,000
  • Area Codes: 803, 839
  • Zip Codes: 29730, 29732, 29733
  • Latitude/Longitude: 34.9246° N, 81.0251° W

Location and History

Rock Hill is located in the northwestern part of South Carolina, near the border with North Carolina. Founded in the late 19th century, it has grown from a small town into one of the largest cities in the state. Rock Hill has a diverse economy that includes manufacturing, education, and retail. It is home to Winthrop University and has a vibrant cultural scene. The city’s growth has been driven by its proximity to Charlotte, North Carolina, and its development as a regional economic and educational center.

Major Landmarks

  • Winthrop University: A public university with a beautiful campus and various cultural events.
  • Glencairn Gardens: A park featuring botanical gardens, walking trails, and seasonal events.
  • Old Town Rock Hill: A revitalized historic district with shops, restaurants, and cultural events.
  • Main Street Children’s Museum: Provides interactive exhibits and educational activities for children.
  • Catawba River: Offers recreational opportunities such as boating, fishing, and scenic views.

Major Highways

Rock Hill is connected by several major highways that support regional and interstate travel. Interstate 77 (I-77) runs north-south through the city, linking Rock Hill to Charlotte, North Carolina, and Columbia, South Carolina. U.S. Route 21 (US 21) runs north-south, providing additional connectivity to surrounding areas. U.S. Route 501 (US 501) runs east-west, connecting Rock Hill to other parts of South Carolina. These highways are essential for transportation and support Rock Hill’s role as a regional economic and educational hub.

6. Greenville (South Carolina)

City Facts

  • County: Greenville
  • Area: 45.35 sq mi
  • Population: Approximately 75,000
  • Area Codes: 864
  • Zip Codes: 29601, 29605, 29607, 29609, 29611, 29615
  • Latitude/Longitude: 34.8526° N, 82.3940° W

Location and History

Greenville, located in the northwestern part of South Carolina, has grown into a vibrant city known for its dynamic downtown area and economic development. Founded in the early 19th century, Greenville has transformed from a small mill town into a major economic and cultural center. The city is recognized for its revitalized downtown, cultural events, and emphasis on quality of life. Greenville’s growth has been fueled by its strong economy, attractive living conditions, and a focus on urban redevelopment and sustainability.

Major Landmarks

  • Falls Park on the Reedy: A scenic park featuring waterfalls, walking trails, and a pedestrian suspension bridge.
  • Greenville Zoo: Offers a range of animal exhibits and educational programs.
  • The Peace Center: A performing arts venue hosting concerts, theater productions, and other events.
  • Swamp Rabbit Trail: A multi-use trail for walking, running, and biking.
  • Bob Jones University Museum & Gallery: Features a collection of religious art and historical exhibits.

Major Highways

Greenville is served by several major highways that facilitate regional and interstate travel. Interstate 85 (I-85) runs north-south through the city, linking Greenville to Atlanta, Georgia, and Charlotte, North Carolina. U.S. Route 29 (US 29) runs north-south, providing additional connectivity to surrounding areas. Interstate 385 (I-385) provides east-west access to Columbia and the upstate region of South Carolina. These highways are vital for transportation and support Greenville’s role as a regional economic and cultural center.

7. Spartanburg (South Carolina)

City Facts

  • County: Spartanburg
  • Area: 49.56 sq mi
  • Population: Approximately 40,000
  • Area Codes: 864
  • Zip Codes: 29301, 29302, 29303, 29306, 29307, 29316
  • Latitude/Longitude: 34.9495° N, 81.9320° W

Location and History

Spartanburg, located in the upstate region of South Carolina, is known for its rich history and role as a regional economic center. Founded in the late 18th century, Spartanburg has developed into a city with a diverse economy that includes manufacturing, education, and healthcare. The city is home to several higher education institutions and has a growing cultural scene. Spartanburg’s growth has been driven by its strategic location and its focus on community development and economic expansion.

Major Landmarks

  • Spartanburg Regional History Museum: Offers exhibits on the local history and heritage of Spartanburg.
  • Hatcher Garden and Woodland Preserve: A public garden with walking trails, ponds, and educational programs.
  • Cowpens National Battlefield: A historic site commemorating a key battle in the American Revolution.
  • Chapman Cultural Center: A facility offering arts performances, exhibitions, and educational programs.
  • The Hub City Writers Project: Supports local authors and literary events in the area.

Major Highways

Spartanburg is well-connected by several major highways that support regional and interstate travel. Interstate 85 (I-85) runs north-south through the city, linking Spartanburg to Charlotte, North Carolina, and Atlanta, Georgia. Interstate 26 (I-26) runs east-west, providing access to Columbia and other parts of South Carolina. U.S. Route 29 (US 29) runs north-south, offering additional connectivity to surrounding areas. These highways are crucial for transportation and support Spartanburg’s role as a key city in the upstate region.

8. Sumter (South Carolina)

City Facts

  • County: Sumter
  • Area: 20.27 sq mi
  • Population: Approximately 40,000
  • Area Codes: 803
  • Zip Codes: 29150, 29151, 29152
  • Latitude/Longitude: 33.9209° N, 80.3412° W

Location and History

Sumter, located in central South Carolina, has a rich history dating back to its founding in the early 19th century. The city is known for its role as a regional center for commerce and industry. Sumter’s economy has historically been driven by agriculture, manufacturing, and retail. The city’s growth has been supported by its strategic location along major transportation routes and its focus on community development and economic diversification. Sumter also has a significant military presence with Shaw Air Force Base located nearby.

Major Landmarks

  • Sumter County Museum: Features exhibits on the local history and culture of Sumter County.
  • Swan Lake Iris Gardens: A public garden known for its collection of irises and scenic beauty.
  • Sumter Opera House: A historic theater hosting a range of performances and cultural events.
  • Poinsett State Park: Offers recreational activities such as hiking, fishing, and camping.
  • Shaw Air Force Base: A major military installation contributing to the local economy and community.

Major Highways

Sumter is connected by several key highways that facilitate regional and interstate travel. U.S. Route 76 (US 76) runs east-west through the city, linking Sumter to Columbia and Florence. U.S. Route 521 (US 521) runs north-south, providing connectivity to nearby cities and regions. Interstate 95 (I-95) is accessible via U.S. Route 76, offering north-south connectivity along the eastern seaboard. These highways are essential for transportation and support Sumter’s role as a regional economic and military hub.

9. Aiken (South Carolina)

City Facts

  • County: Aiken
  • Area: 30.28 sq mi
  • Population: Approximately 35,000
  • Area Codes: 803
  • Zip Codes: 29801, 29803, 29805
  • Latitude/Longitude: 33.5616° N, 81.7160° W

Location and History

Aiken, located in western South Carolina near the Georgia border, is known for its historic charm and role as a center for equestrian activities. Founded in the late 19th century, Aiken became a popular winter destination for wealthy northerners and is known for its well-preserved historic district and cultural events. The city has a strong focus on the arts, historic preservation, and community activities. Aiken’s growth has been supported by its appeal as a residential community and its active cultural scene.

Major Landmarks

  • Aiken Thoroughbred Racing Hall of Fame and Museum: Highlights the city’s history in horse racing and equestrian sports.
  • Hopelands Gardens: A public garden featuring walking paths, fountains, and seasonal events.
  • Aiken County Historical Museum: Offers exhibits on the history and heritage of Aiken County.
  • The Aiken Center for the Arts: Features art exhibits, performances, and cultural events.
  • The Big Red Barn: A venue for equestrian events and community gatherings.

Major Highways

Aiken is connected by several major highways that support regional and interstate travel. U.S. Route 1 (US 1) runs north-south through the city, linking Aiken to Augusta, Georgia, and the northern parts of South Carolina. U.S. Route 78 (US 78) runs east-west, providing access to Columbia and other regions of South Carolina. Interstate 20 (I-20) is accessible via U.S. Route 1, offering connectivity to Atlanta, Georgia, and the eastern seaboard. These highways are essential for transportation and support Aiken’s role as a regional center for commerce and culture.

10. Florence (South Carolina)

City Facts

  • County: Florence
  • Area: 33.62 sq mi
  • Population: Approximately 40,000
  • Area Codes: 843
  • Zip Codes: 29501, 29502, 29505, 29506
  • Latitude/Longitude: 34.1950° N, 79.7626° W

Location and History

Florence, located in northeastern South Carolina, has grown into a significant regional center known for its commercial and industrial activities. Founded in the late 19th century, Florence developed as a transportation hub with the arrival of the railroad. The city’s growth has been driven by its strategic location along major transportation routes and its focus on economic development and regional commerce. Florence is known for its vibrant downtown area, historical sites, and community-oriented events.

Major Landmarks

  • Florence County Museum: Offers exhibits on local history, art, and culture.
  • Pride Park: A community park featuring recreational facilities, walking trails, and events.
  • The Florence Little Theatre: Hosts a range of performances and community events.
  • Timrod Park: Provides green space, walking trails, and picnic areas.
  • Palmetto Peddler Antique Mall: Features a variety of antiques and collectibles.

Major Highways

Florence is served by several major highways that facilitate regional and interstate travel. Interstate 95 (I-95) runs north-south through the city, linking Florence to Richmond, Virginia, and Miami, Florida. Interstate 20 (I-20) runs east-west, providing access to Columbia and other parts of South Carolina. U.S. Route 52 (US 52) runs north-south, offering additional connectivity to surrounding areas. These highways are crucial for transportation and support Florence’s role as a key commercial and transportation hub in the region.